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2024-09-25

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개요

• 장기이식코호트는 국내 5개 장기(신장, 간, 심장, 폐, 췌장)이식 및 해외 신장 이식에 대한 코호트를 확립하고 이식 후 장기이식과 관련된 임상정보, 생존률 등에 영향을 미칠 수 있는 환경적 요인 등에 대한 추적 조사연구를 수행하는 코호트 사업입니다.

추진 경과

• 2014년부터 장기이식코호트를 구축하여 운영 중이며, 코호트를 통해 수여자 및 공여자의 임상정보 및 인체자원 수집 중이며, 2020년부터 해외 신장이식에 대한 코호트 구축을 위해 온라인 데이터 입력 플랫폼을 확보하고 임상정보를 수집 중입니다.
• 현재 국내 5개 장기의 86개 센터가 장기이식코호트에 참여 중이며, 해마다 약 2,000건 이상의 신규 이식 대상자를 등록 진행중입니다.
• 매년 전문가용 및 일반인용 연차보고서를 발간하여 국민들의 장기이식에 대한 이해를 높이고 코호트 연구에 참여하지 않은 전문가들에게 장기이식 환자의 치료에 도움이 되는 정보를 제공하고 있습니다.

주요 성과

• 장기이식코호트 수집 자료를 활용하여 2019년부터 2023년 12월까지 총 55편의 연구논문이 발표되었습니다. 장기이식 관련 자료는 장기이식코호트 연차보고서를 참고하시기 바랍니다.

  장기이식코호트 수집 자료 제목 다운로드 으로 구성

  제목	다운로드
  장기이식코호트 KOTRY 연차보고서(일반인용)	다운로드
  장기이식코호트 KOTRY 연차보고서(전문가용)	다운로드

• 논문목록
  • 2023년
  • 2022년
  • 2021년
  • 2020년
  • 2019년

  해당 관련 논문목록과 초록보기 링크 제공

  Gender Disparity in Asian-Pacific Countries: An Analysis of the ASTREG-WIT-KT Registry Transplantation	초록보기
  Time-varying risk factors for incident fractures in kidney transplant recipients: A nationwide cohort study from South Korea Journal of Clinical Medicine	초록보기
  Physical Performance Decline During the Early Posttransplantation Period Affects Survival After Living Donor Liver Transplantation Transplantation	초록보기
  Clinical implications of changes in metabolic syndrome status after kidney transplantation: a nationwide prospective cohort study Nephrology Dialysis Transplantation	초록보기
  Quantitative prediction of posttransplant hepatocellular carcinoma prognosis using ADV score: Validation with Korean Organ Transplantation Registry database Journal of gastrointestinal surgery	초록보기
  Evaluating Anti-thymocyte Globulin Induction Doses for Better Allograft and Patient Survival in Asian Kidney Transplant Recipients Scientific reports	초록보기
  Outcomes and risk factors for liver transplantation using graft-to-recipient weight ratio less than 0.8 graft from living donors: multicentric cohort study Annals of Surgery, Online ahead	초록보기
  Entecavir versus tenofovir on recurrence of hepatitis B-related hepatocellular carcinoma after liver transplantation: Multicenter observational study Liver Transplantation	초록보기
  Clinical significance of the Living kidney donor profile index in living kidney donors for predicting of post-transplant long term outcome: Korean Organ Transplantation Registry Kidney Research and Clinical Practice, Online ahead	초록보기
  The effect of donor against recipient one-way HLA mismatch on liver transplantation outcomes from a multicenter registry analysis scientific reports	초록보기

  해당 관련 논문목록과 초록보기 링크 제공

  Impact of predicted heart mass-based size matching on survival after heart transplantation in Korea: Analysis of the Korean Organ Transplant Registry The journal of heart and lung transplantation	초록보기
  Diagnostic role of tumor markers for hepatocellular carcinoma in liver transplantation candidates: An analysis using Korean Organ Transplantation Registry database Annals of Transplantation	초록보기
  Comparison of mid-term clinical outcome in heart transplantation patients using mycophenolate mofetil versus enteric-coated mycophenolate sodium Frontiers in Cardiovascular medicine	초록보기
  Comparison of Early and Late Pneumocystis jirovecii Pneumonia in Kidney Transplant Patients - the Korean Organ Transplantation Registry (KOTRY) Study Scientific reports	초록보기
  Impact of donor hypertension on graft survival and function in living and deceased donor kidney transplantation: a nationwide prospective cohort study Journal of Hypertension	초록보기
  Safety of tacrolimus monotherapy within 12 months after liver transplantation in the era of reduced tacrolimus and mycophenolate mofetil:national registry study Journal of clinical medicine	초록보기
  Artificial intelligence for predicting survival following deceased donor liver transplantation: Retrospective multi-center study International Journal of Surgery	초록보기
  Effect of pretransplant dialysis vintage on clinical outcomes in deceased donor kidney transplant Scientific Reports	초록보기
  Non-renal risk factors for chronic kidney disease in liver recipients with functionally intact kidneys at 1 month Journal of clinical medicine	초록보기
  Personalized Prediction of Kidney Function Decline and Network Analysis of the Risk Factors after Kidney Transplantation Using Nationwide Cohort Data Journal of clinical medicine	초록보기

  해당 관련 논문목록과 초록보기 링크 제공

  Changes in renal function and predictors affecting renal outcome of living kidney donors from a nationwide prospective cohort Nephrology	초록보기
  Outcomes of ABO-incompatible kidney transplantation in older patients: a national cohort study Transplant International	초록보기
  The Comparative Study of Postoperative Outcomes Between Minimally Invasive Living Donor Hepatectomy and Open Living Donor Hepatectomy : The Korean Organ Transplantation Registry Surgery	초록보기
  Primary Graft Dysfunction after Isolated Heart Transplantation: Incidence, Risk Factors, and Clinical Implications Circulation Journal	초록보기
  Outcomes after Liver Transplantation in Korea: Incidence and Risk Factors from Korean Transplantation Registry Clinical and molecular Hepatology	초록보기
  Impact of acute kidney injury on graft outcomes in deceased donor kidney transplantation: a nationwide registry-based matched cohort study in Korea Transplant International	초록보기
  Declining trends of preemptive kidney transplantation and impact of pre-transplant dialysis: a Korean nationwide prospective cohort study Transplantation	초록보기
  Impact of preoperative renal replacement therapy on the clinical outcome of heart transplant patients Scientific reports	초록보기
  Lung transplantation for patients with severe COVID-19-related ARDS in Korea Therapeutic Advances in Respiratory Disease	초록보기
  Korean Organ Transplantation RegistrY (KOTRY): Overview and Summary of Kidney Transplant Cohort Kidney Research and Clinical Practice	초록보기
  Anti-thymocyte globulin versus basiliximab induction for kidney transplantation in older patients: Matched analysis with Korean multicentric registry Kidney Research and Clinical Practice	초록보기
  Liver transplantation for young adult patients with post-Kasai portoenterostomy biliary atresia: Analysis of Korean Organ Transplantation Registry database Annals of Liver Transplantation	초록보기
  Risk for coexistence of ABO incompatibility and donor-recipient weight mismatch in living donor kidney transplantation: a national cohort study Jounal of Clinical Medicine	초록보기
  Impact of acute kidney injury on graft outcomes in deceased donor kidney transplantation : a nationwide registry-based matched cohort study in korea Plos One	초록보기
  Renal safety of tenofovir disoproxil fumarate and entecavir in liver transplant patients: a nationwide Korean registry study Hepatology International	초록보기
  The assessment and outcomes of crossmatching in lung transplantation in Korean patients Journal of Korean Medical Science	초록보기

  해당 관련 논문목록과 초록보기 링크 제공

  Hepatitis B Prophylaxis after Liver Transplantation in Korea: Analysis of the KOTRY Database Journal of Korean Medical Science	초록보기
  Panel-Reactive and Donor-Specific Antibodies before Lung Transplantation can Affect Outcomes in Korean Patients Receiving Lung Transplantation Yonsei medical journal	초록보기
  Kidney Donor Risk Index (KDRI) score is more reliable than Kidney Donor Profile Index (KDPI) in kidney transplantation from elderly deceased donors. Transplantation proceedings	초록보기
  Outcomes of Pediatric Liver Transplantation in Korea Using Two National Registries Journal of Clinical Medicine	초록보기
  Epidemiology, risk factors, and clinical impact of early post-transplant infection in older kidney transplant recipients: The Korean Organ Transplantation Registry Study BMC geriatrics	초록보기
  Dominant predictors for the early outcomes of kidney transplantation: The Korean Organ Transplantation Registry (KOTRY) report of Korean kidney transplantation 5 years outcome Scientific Reports	초록보기
  Synergistic impact of pre-sensitization and delayed graft function on allograft rejection in deceased donor kidney transplantation Scientific Reports	초록보기
  New-onset diabetes after adult liver transplantation in the Korean Organ Transplantation Registry (KOTRY) study Hepatobiliary Surgery and Nutrition	초록보기
  Extracorporeal membrane oxygenation as a bridge to lung transplantation: analysis of Korean organ transplantation registry (KOTRY) data Respiratory Research	초록보기
  Outcomes of kidney transplantation from elderly deceased donors of a Korean registry PLOS ONE	초록보기
  The tacrolimus metabolism affect post-transplant outcome mediating acute rejection and delayed graft function: analysis from Korean Organ Transplantation Registry (KOTRY) data Transplantation International	초록보기
  Development of the Asian Transplant Registry Under the Asian Society of Transplantation Transplantation proceedings	초록보기

  해당 관련 논문목록과 초록보기 링크 제공

  Effect of simultaneous presence of anti-blood group A/B and -HLA antibodies on clinical outcomes in kidney transplantation across positive crossmatch: a nationwide cohort study Scientific reports	초록보기
  Validation of Identified Susceptible Gene Variants for New-Onset Diabetes in Renal Transplant Recipients Journal of Clinical Medicine	초록보기
  Characteristics of lung allocation and outcomes of lung transplant according to the Korean urgency status Yonsei medical journal	초록보기
  Real-world hepatitis B prophylaxis after liver transplantation in Korea: analysis of KOTRY Database Journal of Korean Medical Science	초록보기
  Clinical outcomes of kidney transplantation in older end‐stage renal disease patients: A nationwide cohort study Geriatrics and Gerontology international	초록보기
  The Korean Organ Transplant Registry (KOTRY): Second Official Adult Heart Transplant Report Korean Circulation Journal	초록보기

주요 자원 현황

• 현재 장기이식코호트 연구자원의 경우 비공개로 되어 있으며, 공개를 위해 진행 중에 있습니다.