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연구자원
국립줄기세포재생센터
- 수정일
- 2024-09-26
분양가능 세포주 목록
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분양가능 세포주 목록의 종류 세포주 명 기탁기관 유래 및 수립방법 배양조건 특성분석결과 NGS data 참고문헌 으로 구성 종류 세포주 명 기탁기관 유래 및 수립방법 배양조건 특성분석
결과NGS
data참고문헌 hESC SNUhES3 서울대학교 ㆍOrigin: human embryo
ㆍ등록번호 : hES12010005ㆍFeeder (STO)
ㆍhPSC mediaPDF다운로드 SNUhES4 서울대학교 ㆍOrigin: human embryo
ㆍ등록번호 : hES12010006ㆍFeeder (STO)
ㆍhPSC mediaPDF다운로드 SNUhES31 서울대학교 ㆍOrigin: human embryo
ㆍ등록번호 : hES12010037ㆍFeeder-free
ㆍVN-E8PDF다운로드 CHA-hES15 차의과학대학교 ㆍOrigin: human embryo
ㆍ등록번호 : hES12010028ㆍFeeder (STO)
ㆍhPSC mediaPDF다운로드 hiPSC
(healty donor cell-derived)hFmiPS1 국립보건연구원 ㆍParental cell : Dermal fibroblast
ㆍReprogram : modified RNA
ㆍAbnormal karyotypeㆍFeeder (STO)
ㆍhPSC mediaPDF다운로드 hFmiPS2 국립보건연구원 ㆍParental cell : Dermal fibroblast
ㆍReprogram : modified RNAㆍFeeder-free
ㆍVN-E8PDF다운로드 hFSiPS3-1 국립보건연구원 ㆍParental cell : Dermal fibroblast
ㆍReprogram : Sendai virus
ㆍhFSiPS1 sub-lineㆍFeeder-free
ㆍVN-E8PDF다운로드 hUSiPS2 국립보건연구원 ㆍParental cell : Urinal cell
ㆍReprogram : Sendai virusㆍFeeder-free
ㆍVN-E8PDF다운로드 hAdMSiPS1 국립보건연구원 ㆍParental cell : Adipocyte-MSC, TALEN
ㆍReprogram : Sendai virusㆍFeeder (STO)
ㆍhPSC mediaPDF다운로드 CMC-hiPSC-003 가톨릭대학교 ㆍParental cell : Bone marrow
ㆍReprogram : Sendai virus
ㆍHLA-homozygoteㆍFeeder-free
ㆍVN-E8PDF다운로드 CMC-hiPSC-005 가톨릭대학교 ㆍParental cell : Cord blood
ㆍReprogram : Sendai virus
ㆍHLA-homozygote
ㆍAbnormal karyotypeㆍFeeder-free
ㆍVN-E8PDF다운로드 CMC-hiPSC-009 가톨릭대학교 ㆍParental cell : Cord blood
ㆍReprogram : Sendai virus
ㆍHLA-homozygoteㆍFeeder-free
ㆍVN-E8PDF다운로드 CMC-hiPSC-011 가톨릭대학교 ㆍParental cell : Cord blood
ㆍReprogram : Sendai virus
ㆍHLA-homozygoteㆍFeeder-free
ㆍVN-E8PDF다운로드 CMC-hiPSC-022 가톨릭대학교 ㆍParental cell : Cord blood
ㆍReprogram : Sendai virus
ㆍHLA-homozygoteㆍFeeder-free
ㆍVN-E8PDF다운로드 NU01-EiPS07 국립보건연구원 ㆍParental cell : Urinal cell
ㆍReprogram : Episomal vectorㆍFeeder-free
ㆍVN-E8PDF다운로드 PB01-EiPS21 국립보건연구원 ㆍParental cell : Peripheral blood cell
ㆍReprogram : Episomal vectorㆍFeeder-free
ㆍVN-E8PDF다운로드 Disease
-Specific
hiPSCDKH005i-A 국립보건연구원 ㆍParental cell : Peripheral blood cell
ㆍReprogram : Sendai virus
ㆍDisease : Eye disease, Senior Loken syndromeㆍFeeder-free
ㆍVN-E8PDF다운로드 DKH090i-A 국립보건연구원 ㆍParental cell : Peripheral blood
ㆍReprogram : Sendai virus
ㆍDisease : Eye disease, Leber congenital amaurosisㆍFeeder-free
ㆍVN-E8PDF다운로드 LQT01-hiPSC 국립보건연구원 ㆍParental cell : Peripheral blood
ㆍReprogram : Sendai virus
ㆍDisease : Heart-signaling disorder, long QT syndrome type 2, KCNH2 (c.453delC)ㆍFeeder-free
ㆍVN-E8PDF다운로드 LQT08-hiPSC 국립보건연구원 ㆍParental cell : Peripheral blood
ㆍReprogram : Sendai virus
ㆍDisease : Heart-signaling disorder, long QT syndrome type 1, Brugada syndrome, KCNQ1 (c.569G>A)ㆍFeeder-free
ㆍVN-E8PDF다운로드 Fluorescent
protein-tagged hiPSCNCRM5AS1-iCAGcGFP.c9 NIH-CRM
(미국)ㆍGenetic modification (GFP), TALEN
ㆍParental cell : Peripheral blood (CD34+)
ㆍReprogram : Episomal vectorㆍFeeder-free
ㆍVN-E8PDF다운로드 CMC-003i-Nestin.EGFP 국립보건연구원 ㆍGenetic modification (EGFP in Nestin gene), CRISPR/CAS9
ㆍParental cell : CMC-hiPSC-003ㆍFeeder-free
ㆍVN-E8PDF다운로드 CMC-003i-Pdx1.EGFP 국립보건연구원 ㆍGenetic modification (EGFP in PDX1 gene), CRISPR/CAS9
ㆍParental cell : CMC-hiPSC-003ㆍFeeder-free
ㆍVN-E8PDF다운로드 PB01-EiPS21
(GFP-NLS7)국립보건연구원 ㆍGenetic modification (EGFP-NLS in AAVS1 site), CRISPR/CAS9
ㆍParental cell : PB01-EiPS21ㆍFeeder-free
ㆍStemFlexPDF다운로드 PB01-EiPS21(Ruby2) 국립보건연구원 ㆍGenetic modification (Ruby in AAVS1 site), CRISPR/CAS9
ㆍParental cell : PB01-EiPS21ㆍFeeder-free
ㆍStemFlexPDF다운로드 PB01-EiPS21-EGFP04 국립보건연구원 ㆍGenetic modification (EGFP in AAVS1 site), CRISPR/CAS9
ㆍParental cell : PB01-EiPS21ㆍFeeder-free
ㆍVN-E8PDF다운로드 PB01-EiPS21-EGFP05 국립보건연구원 ㆍGenetic modification (EGFP in AAVS1 site), CRISPR/CAS9
ㆍParental cell : PB01-EiPS21ㆍFeeder-free
ㆍVN-E8PDF다운로드 Gene-Edited hiPSC hiPSC-TLR2KO 국립보건연구원 ㆍGenetic modification (TLR2 knock-out), CRISPR/CAS9
ㆍ(parental cell) modified from hiPSC CMC-hiPSC-003
ㆍParental cell : CMC-hiPSC-003ㆍFeeder-free
ㆍVN-E8PDF다운로드 hiPSC-TLR3KO-A49 국립보건연구원 ㆍGenetic modification (TLR3 knock-out), CRISPER/CAS9
ㆍParental cell : CMC-hiPSC-003ㆍFeeder-free
ㆍVN-E8PDF다운로드 hiPSC-TLR7KO-A59 국립보건연구원 ㆍGenetic modification (TLR7 knock-out), CRISPER/CAS9
ㆍParental cell : CMC-hiPSC-003ㆍFeeder-free
ㆍVN-E8PDF다운로드 hiPSC-TLR8KO-A10 국립보건연구원 ㆍGenetic modification (TLR8 knock-out), CRISPER/CAS9
ㆍParental cell : CMC-hiPSC-003ㆍFeeder-free
ㆍVN-E8PDF다운로드 hFSiPS1_DUSP6KO 국립보건연구원 ㆍGenetic modification (DUSP6 knock-out), CRISPR/CAS9
ㆍParental cell : hFSiPS1ㆍFeeder-free
ㆍVN-E8PDF다운로드 hFSiPS1_DUSP6KOA 국립보건연구원 ㆍGenetic modification (DUSP6 knock-out), CRISPR/CAS9
ㆍParental cell : hFSiPS1
hFSiPS1_DUSP6KO sublineㆍFeeder-free
ㆍVN-E8PDF다운로드
분양 안내
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분양을 원하시는 분은 아래 연락처로 연락 부탁드립니다.
- 난치성질환과 : nscb@korea.kr
NGS data - NU01-EiPS07
| 종류 | 링크 |
|---|---|
| SNP chip(CNV) | 외부링크연결 |
| WES(SNP&INDEL) | |
| RNA-seq | |
| Methyl-seq |
hESC
| 종류 | 세포주 명 | 참고문헌 | DOI Link |
|---|---|---|---|
| hESC | SNUhES3 | Oh SK et al. Derivation and characterization of new human embryonic stem cell lines: SNUhES1, SNUhES2, SNUhES3. Stem Cells. 2005 Feb;23(2):211-9. | 외부링크연결 |
| Lee J-Y et al. Registration of human embryonic stem cell lines: Korea, 2010. Osong Public Health Res Perspect. 2011 Sep;2(2):141-7. | 외부링크연결 | ||
| Kim JH et al. Korea National Stem Cell Bank. Stem Cell Res. 2021 May;53:102270. | 외부링크연결 | ||
| SNUhES4 | Lee J-Y et al. Registration of human embryonic stem cell lines: Korea, 2010. Osong Public Health Res Perspect. 2011 Sep;2(2):141-7. | 외부링크연결 | |
| Kim JH et al. Korea National Stem Cell Bank. Stem Cell Res. 2021 May;53:102270. | 외부링크연결 | ||
| SNUhES31 | Lee J-Y et al. Registration of human embryonic stem cell lines: Korea, 2010. Osong Public Health Res Perspect. 2011 Sep;2(2):141-7. | 외부링크연결 | |
| Jo HY et al. Functional in vivo and in vitro effects of 20q11.21 genetic aberrations on hPSC differentiation. Sci Rep. 2020 Oct 29;10(1):18582. | 외부링크연결 | ||
| Kim JH et al. Korea National Stem Cell Bank. Stem Cell Res. 2021 May;53:102270. | 외부링크연결 | ||
| Yoo DH et al. DUSP6 is a memory retention feedback regulator of ERK signaling for cellular resilience of human pluripotent stem cells in response to dissociation. Sci Rep. 2023 Apr 7;13(1):5683. | 외부링크연결 | ||
| CHA-hES15 | Hwnag ST et al. The expansion of human ES and iPSC cells on porous membranes and proliferating human adipose-derived feeder cells. Biomaterials. 2010 Nov;31(31):8012-21. | 외부링크연결 | |
| Lee J-Y et al. Registration of human embryonic stem cell lines: Korea, 2010. Osong Public Health Res Perspect. 2011 Sep;2(2):141-7. | 외부링크연결 | ||
| Kim SJ et al. Generation of hematopoietics stem cells from human embryonic stem cells using a defined, stepwise, serumfree replacement free monolyer culture method. Blood Research. 2017 Mar;52(1):37-43. | 외부링크연결 | ||
| Jo HY et al. Functional in vivo and in vitro effects of 20q11.21 genetic aberrations on hPSC differentiation. Sci Rep. 2020 Oct 29;10(1):18582. | 외부링크연결 | ||
| Kim JH et al. Korea National Stem Cell Bank. Stem Cell Res. 2021 May;53:102270. | 외부링크연결 |
hiPSC(healty donor)
| 종류 | 세포주 명 | 참고문헌 | DOI Link |
|---|---|---|---|
| hiPSC(healty donor) | hFmiPS1 | Uhm KO et al. Generation of human induced pluripotent stem cell lines from human dermal fibroblasts using a modified RNA system. Stem Cell Res. 2017 Oct;24:148-150. | 외부링크연결 |
| Jo HY et al. Functional in vivo and in vitro effects of 20q11.21 genetic aberrations on hPSC differentiation. Sci Rep. 2020 Oct 29;10(1):18582. | 외부링크연결 | ||
| Kim JH et al. Korea National Stem Cell Bank. Stem Cell Res. 2021 May;53:102270. | 외부링크연결 | ||
| hFmiPS2 | Uhm KO et al. Generation of human induced pluripotent stem cell lines from human dermal fibroblasts using a modified RNA system. Stem Cell Res. 2017 Oct;24:148-150. | 외부링크연결 | |
| Jo HY et al. Functional in vivo and in vitro effects of 20q11.21 genetic aberrations on hPSC differentiation. Sci Rep. 2020 Oct 29;10(1):18582. | 외부링크연결 | ||
| Kim JH et al. Korea National Stem Cell Bank. Stem Cell Res. 2021 May;53:102270. | 외부링크연결 | ||
| hFSiPS1/hFSiPS3-1 | Kim JY et al. HDAC6 Inhibitors rescued the defective axonal mitochondrial movement in motor neurons derived from the induced pluripotent stem cells of peripheral neuropathy patient swith HSPB1 Mutation. Stem Cells Int. 2016 2016:9475981. | 외부링크연결 | |
| Uhm KO et al. Generation of human induced pluripotent stem cell lines from human dermal fibroblasts using a non-integration system. Stem Cell Res. 2017 May;21:13-15. | 외부링크연결 | ||
| Choi M et al. Multilayer Nanofilms via inkjet printing for stabilizing growth factor and designing desired cell developments. Adv Healthc Mater. 2017 Jul;6(14). | 외부링크연결 | ||
| Han U et al. Efficient encapsulation and sustained release of basic fibroblast growth factor in nanofilm : extension of the feeding cycle of human induced pluripotent stem cell culture. ACS Appl Mater Interfaces. 2017 Aug 2;9(30):25087-25097. | 외부링크연결 | ||
| Oh M et al. Promotive effects of human induced pluripotent stem cell-conditioned medium on the proliferation and migration of dermal fibroblasts. Biotechnol Bioproc E. 2017 Nov 22, 561-568. | 외부링크연결 | ||
| Oh M et al. Exosomes derived from human induced pluripotent stem cells ameliorate the aging of skin fibroblasts. Int J Mol Sci. 2018 Jun 9;19(6):1715. | 외부링크연결 | ||
| Han U et al. Construction of nano-scale cellular environments by coating a multilayer nanofilm on the surface of human induced pluripotent stem cells. Nanoscale. 2019 Jul 28;11(28):13541-13551. | 외부링크연결 | ||
| Lee H et al. Derivation of Cell-Engineered Nanovesicles from Human Induced Pluripotent Stem Cells and Their Protective Effect on the Senescence of Dermal Fibroblasts. Int J Mol Sci. 2020 Jan 5;21(1):343. | 외부링크연결 | ||
| Kim YK et al. Generation of a GLA knock-out human-induced pluripotent stem cell line, KSBCi002-A-1, using CRISPR/Cas9. Stem Cell Res. 2020 Jan;42:101676. | 외부링크연결 | ||
| Yoo DH et al. Simple differentiation method using FBS identifies DUSP6 as a marker for fine-tuning of FGF-ERK signaling activity in human pluripotent stem cells. Biochem Biophys Res Commun. 2020 Jan 8;521(2):375-382. | 외부링크연결 | ||
| Cha BH et al. Efficient Isolation and enrichment of mesenchymal stem cells from human embryonic stem cells by utilizing the Interaction between integrin α5β1 and fibronectin. Adv Sci (Weinh). 2020 Jul 19;7(17):2001365. | 외부링크연결 | ||
| Jo HY et al. Functional in vivo and in vitro effects of 20q11.21 genetic aberrations on hPSC differentiation. Sci Rep. 2020 Oct 29;10(1):18582. | 외부링크연결 | ||
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특허출원 : 물리적 자극을 통한 심근세포 분화 성숙도 및 기능성 향상 방법, 출원인 : 한국화학연구원, 출원번호 : 10-2020-0189736, 출원일자 : 2020년 12월 31일 |
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| Han U et al. Nano-structure of vitronectin/heparin on cell membrane for stimulating single cell in iPSC-derived embryoid body. iScience. 2021 Mar 11;24(4):102297. | 외부링크연결 | ||
| Kim JH et al. Korea National Stem Cell Bank. Stem Cell Res. 2021 May;53:102270. | 외부링크연결 | ||
| Heo HR et al. Generation of marcrophage containing alveolar organoids derived from humna pluripotent stem cells for pulmonary fibrosis modeling and drug efficacy testing. Cell Biosci. 2021 Dec 18;11(1):216. | 외부링크연결 | ||
| Lee SJ et al. Improving Generation of Cardiac Organoids from Human Pluripotent Stem Cells Using the Aurora Kinase Inhibitor ZM447439. Biomedicines. 2021 Dec 20;9(12):1952. | 외부링크연결 | ||
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특허출원 :오로라 키나아제 억제제를 이용하는 심근세포 및 심장 오가노이드의 제조방법, 출원인 : 한국화학연구원, 출원번호 : 10-2021-0179903, 출원일자 : 2021년 12월 15일 |
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특허출원 : 줄기세포로부터 도파민 신경전구세포 분화 유도 방법, 출원인 : 조명수 등, 출원번호 : 10-2022-0049108, 출원일자 : 2022년 4월 20일 |
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특허출원 : DUSP6가 결핍된 줄기세포 및 이의 용도 (DUSP6 deficient stem cells and their use), 출원인 : 국립보건연구원장, 출원번호 : 10-2022-0073479, 출원일자 : 2022년 6월 16일 |
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| Yoo DH et al. DUSP6 is a memory retention feedback regulator of ERK signaling for cellular resilience of human pluripotent stem cells in response to dissociation. Sci Rep. 2023 Apr 7;13(1):5683. | 외부링크연결 | ||
| hUSiPS2 | Uhm KO et al. Generation of human induced pluripotent stem cells from urinary cells of a healthy donor using a non-integration system. Stem Cell Res. 2017 May;21:44-46. | 외부링크연결 | |
| Jo HY et al. Functional in vivo and in vitro effects of 20q11.21 genetic aberrations on hPSC differentiation. Sci Rep. 2020 Oct 29;10(1):18582. | 외부링크연결 | ||
| Kim JH et al. Korea National Stem Cell Bank. Stem Cell Res. 2021 May;53:102270. | 외부링크연결 | ||
| hAdMSiPS1 | Choi HY et al. Generation of a human induced pluripotent stem cell line, KSCBi003-A, from human adipose tissue-derived mesenchymal stem cells using a chromosomal integration-free system. Stem Cell Res. 2018 Aug;31:1-4. | 외부링크연결 | |
| Kim JH et al. Korea National Stem Cell Bank. Stem Cell Res. 2021 May;53:102270. | 외부링크연결 | ||
| CMC-hiPSC-003 |
특허출원 : HLA 동형접합체의 제대혈단핵구세포 유래 인간전분화능세포를 이용한 연골세포 분화용 조성물 제조방법, 출원인 : 주지현 등, 출원번호 : 10-2017-0178684, 출원일자 : 2017년 12월 22일 |
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| Rim YA et al. Recent progress of national banking project on homozygous HLA-typed induced pluripotent stem cells in South Korea. J Tissue Eng Regen Med. 2018 Mar;12(3):e1531-e1536. | 외부링크연결 | ||
| Lim JJ et al. Maintenance of the PSCs under Xeno-Free and chemically defined culture conditions. Int J Stem Cells. 2019 Nov 30;12(3):484-496. | 외부링크연결 | ||
| Han HW. Drug Discovery Platform Targeting M. tuberculosis with Human Embryonic Stem Cell-Derived Macrophages. Stem Cell Reports. 2019 Dec 10;13(6):980-991. | 외부링크연결 | ||
| Jeong S et al. BMP4 and perivascular cells promote hematopoietic differentiation of human pluripotent stem cells in a differentiation stage-specific manner. Exp Mol Med. 2020 Jan;52(1):56-65. | 외부링크연결 | ||
| Jo HY et al, Development of genetic quality tests for good manufacturing practice-compliant induced pluripotent stem cells and their derivatives. Sci Rep. 2020 Mar 3;10(1):3939. | 외부링크연결 | ||
| Ha TW et al. Characterization of Endoplasmic Reticulum (ER) in Human Pluripotent Stem Cells Revealed Increased Susceptibility to Cell Death upon ER Stress. Cells. 2020 Apr 26;9(5):1078. | 외부링크연결 | ||
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특허출원 : 줄기세포 유래 자연살해세포 및 그 제조방법, 출원인 : 테라베스트, 출원번호 : 10-2020-0096415, 출원일자 : 2020년 7월 31일 |
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| Mun SJ et al. Effect of microbial short-chain fatty acids on CYP3A4-mediated metabolic activation of human pluripotent stem cell-derived liver orgaoids. Cells. 2021 Jan 11;10(1):126. | 외부링크연결 | ||
| Han U et al. Nano-structure of vitronectin/heparin on cell membrane for stimulating single cell in iPSC-derived embryoid body. iScience. 2021 Mar 11;24(4):102297. | 외부링크연결 | ||
| Kim JH et al. Korea National Stem Cell Bank. Stem Cell Res. 2021 May;53:102270. | 외부링크연결 | ||
| Jo HY et al. Single-Cell RNA Sequencing of Human Pluripotent Stem Cell-Derived Macrophages for Quality Control of The Cell Therapy Product.. Front Genet. 2022 Jan 31;12:658862. | 외부링크연결 | ||
| Kook MG et al. Generation of Cortical Brain Organoid with Vascularization by Assembling with Vascular Spheroid. Int J Stem Cells. 2022 Feb 28;15(1):85-94. | 외부링크연결 | ||
| Kim MJ et al. Standard operating protocol of hepatic organoid differentiation from human induced pluripotent stem cells. Organoid. 2022 May 2:e5. | 외부링크연결 | ||
| Kim J et al. Neurotoxicity of phenylalanine on human iPSC-derived cerebral organoids. Mol Genet Metab. 2022 Jun;136(2):132-144. | 외부링크연결 | ||
| Seo HR et al. Human pluripotent stem cell-derived alveolar organoid with macrophages. Int J Mol Sci. 2022 Aug 16;23(16):9211. | 외부링크연결 | ||
| Jung SY et al. Wnt-activating human skin organoid model of atopic dermatitis induced by Staphylococcus aureus and its protective effects by Cutibacterium acnes. iScience. 2022 Sep 16;25(10):105150. | 외부링크연결 | ||
| Kong D et al. Cortical-blood vessel assembloids exhibit Alzheimer's disease phenotypees by activating glia after SARS-CoV-2 infection. Cell Death Discov. 2023 Jan 25;9(1):32. | 외부링크연결 | ||
| CMC-hiPSC-005 |
특허출원 : HLA 동형접합체의 제대혈단핵구세포 유래 인간전분화능세포를 이용한 연골세포 분화용 조성물 제조방법, 출원인 : 주지현 등, 출원번호 : 10-2017-0178684, 출원일자 : 2017년 12월 22일 |
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| Rim YA et al. Recent progress of national banking project on homozygous HLA-typed induced pluripotent stem cells in South Korea. J Tissue Eng Regen Med. 2018 Mar;12(3):e1531-e1536. | 외부링크연결 | ||
| Kim JH et al. Korea National Stem Cell Bank. Stem Cell Res. 2021 May;53:102270. | 외부링크연결 | ||
| CMC-hiPSC-009 |
특허출원 : HLA 동형접합체의 제대혈단핵구세포 유래 인간전분화능세포를 이용한 연골세포 분화용 조성물 제조방법, 출원인 : 주지현 등, 출원번호 : 10-2017-0178684, 출원일자 : 2017년 12월 22일 |
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| Rim YA et al. Recent progress of national banking project on homozygous HLA-typed induced pluripotent stem cells in South Korea. J Tissue Eng Regen Med. 2018 Mar;12(3):e1531-e1536. | 외부링크연결 | ||
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특허출원 : 세포 비접착성 PEG 고분자 기판 상에 형성된 심근세포 스페로이드 및 이의 제조방법, 출원인 : 이재혁 등, 출원번호 : 10-2019-0160657, 출원일자 : 2019년 12월 05일 |
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| Jeong S et al. BMP4 and perivascular cells promote hematopoietic differentiation of human pluripotent stem cells in a differentiation stage-specific manner. Exp Mol Med. 2020 Jan;52(1):56-65. | 외부링크연결 | ||
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특허출원 : 줄기세포 유래 자연살해세포 및 그 제조방법, 출원인 : 테라베스트, 출원번호 : 10-2020-0096415, 출원일자 : 2020년 7월 31일 |
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| Kim MJ et al. Standard operating protocol of hepatic organoid differentiation from human induced pluripotent stem cells. Organoid. 2022 May 2:e5. | 외부링크연결 | ||
| CMC-hiPSC-011 |
특허출원 : HLA 동형접합체의 제대혈단핵구세포 유래 인간전분화능세포를 이용한 연골세포 분화용 조성물 제조방법, 출원인 : 주지현 등, 출원번호 : 10-2017-0178684, 출원일자 : 2017년 12월 22일 |
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| Rim YA et al. Recent progress of national banking project on homozygous HLA-typed induced pluripotent stem cells in South Korea. J Tissue Eng Regen Med. 2018 Mar;12(3):e1531-e1536. | 외부링크연결 | ||
| Kim Y et al. Establishment of a complex skin structure via layered co-culture of keratinocytes and fibroblasts derived from induced pluripotent stem cells. Stem Cell Res Ther. 2018 Aug 13;9(1):217. | 외부링크연결 | ||
| 특허출원 : 인간 만능줄기세포로부터 제작된 3D 오가노이드를 해체하여 세포를 다량 확보하는 분화방법, 출원인 : 이상훈 등, 출원번호 : 10-2019-0128602, 출원일자 : 2019년 10월 16일 |
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| Jeong S et al. BMP4 and perivascular cells promote hematopoietic differentiation of human pluripotent stem cells in a differentiation stage-specific manner. Exp Mol Med. 2020 Jan;52(1):56-65. | 외부링크연결 | ||
| Choi SW et al. Antiviral activity and safety of remdesivir against SARS-CoV-2 infection in human pluripotent stem cell-derived cardiomyocytes. Antiviral Res. 2020 Dec;184:104955. | 외부링크연결 | ||
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특허출원 : 인간만능줄기세포로부터 제작된 3D 오가노이드를 해체하여 세포를 다량 확보하는 분화방법, 출원인 : 이상훈 등, 출원번호 : PCT/KR2020/000581, 출원일자 : 2020년 1월 13일 |
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특허출원 : 인간 전분화능줄기세포 유래 심근세포를 이용한 SARS-CoV-2 바이러스 대상 후보 약물의 부정맥 위험성 평가용 조성물 및 이를 이용한 부정맥 위험성 평가 방법, 출원인 : 문성환 등, 출원번호 : 10-2020-0081612, 출원일자 : 2020년 7월 2일 |
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특허출원 : 인간 전분화능줄기세포 유래 심근세포를 이용한 SARS-CoV-2 바이러스 대상 후보 약물의 심근세포 독성평가용 조성물 및 이를 이용한 심근세포 독성 평가 방법, 출원인 : 문성환 등, 출원번호 : 10-2020-0084634, 출원일자 : 2020년 7월 9일 |
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특허출원 : 동결보관 및 저산소 조건에서의 생존율을 향상시키는 심근세포 응집체 제작 기술, 출원인 : 문성환 등, 출원번호 : 10-2020-0091585, 출원일자 : 2020년 7월 23일 |
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특허출원 : 동결보관 및 저산소 조건에서의 생존율을 향상시키는 심근세포 응집체 제작 기술, 출원인 : 문성환 등, 출원번호 : PCT/KR2020/011077, 출원일자 : 2020년 8월 14일 |
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특허출원 : 인간 전분화능줄기세포 유래 심근세포를 이용한 SARS-CoV-2 바이러스 대상 후보 약물의 심근세포 독성평가용 조성물 및 이를 이용한 심근세포 독성 평가 방법, 출원인 : 문성환 등, 출원번호 : PCT/KR2020/016771, 출원일자 : 2020년 11월 25일 |
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특허출원 : 인간 전분화능줄기세포 유래 심근세포를 이용한 SARS-CoV-2 바이러스 대상 후보 약물의 부정맥 위험성 평가용 조성물 및 이를 이용한 부정맥 위험성 평가 방법, 출원인 : 문성환 등, 출원번호 : PCT/KR2020/016777, 출원일자 : 2020년 11월 25일 |
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특허등록 : 동결보관 및 저산소 조건에서의 생존율을 향상시키는 심근세포 응집체 제작 기술, 등록인 : 문성환 등, 등록번호 : 10-2188256, 등록일자 : 2020년 12월 02일 |
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| Kim JH et al. Korea National Stem Cell Bank. Stem Cell Res. 2021 May;53:102270. | 외부링크연결 | ||
| Oh J, et al Establishment of a novel human iPSC line (YCMi003-A) from a patient with dilated cardiomyopathy carrying genetic varient LMNA p.Asp364His. Stem Cell Res. 2021 Oct;56:102508. | 외부링크연결 | ||
| Lee SH et al. Generation of a human induced pluripotent stem cell line YCMi004-A from a patient with dilated cardiomyopathy carrying a protein-truncating mutation of the Titin gene and its differentiation towards cardiomyocytes. Stem Cell Res. 2021 Dec 16;59:102629. | 외부링크연결 | ||
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특허출원 : 인간 전분화능줄기세포 유래 심근세포를 이용한 약물의 부정맥 위험성 평가 방법, 출원인 : 문성환 등, 출원번호 : 10-2021-0071052, 출원일자 : 2021년 6월 1일 |
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특허출원 : 인간 전분화능줄기세포 유래 심근세포를 이용한 약물의 부정맥 위험성 평가 방법, 출원인 : 문성환 등, 출원번호 : PCT/KR2021/008305, 출원일자 : 2021년 6월 30일 |
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| Park SJ et al. Effect and application of cryopreserved three-dimensional microcardiac spheroids in myocardial infarction therapy. Clin Transl Med. 2022 Jan;12(1):e721. | 외부링크연결 | ||
| Ye E et al. Effect of duty cycles of tumor-treating fields on glioblastoma cells and normal brain organoids,International journal of oncology. Int J Oncol. 2022 Jan;60(1):8. | 외부링크연결 | ||
| Kook MG et al. Generation of Cortical Brain Organoid with Vascularization by Assembling with Vascular Spheroid. Int J Stem Cells. 2022 Feb 28;15(1):85-94. | 외부링크연결 | ||
| Cha YJ et al. Derivation of YCMi005-A, a human-induced pluripotent stem cell line, from a patient with dilated cardiomyopathy carrying missense variant in TPM1(p.Glu192Lys). Stem Cell Res. 2022 Apr;60:102707. | 외부링크연결 | ||
| Lee JY et al. Human palatine tonsils are linked to alzheimer's disease through function of reservoir of amyloid beta protein associated with bacterial infection. Cells. 2022 Jul 24;11(15):2285. | 외부링크연결 | ||
| Kang JY et al. Generation of a heterozygous TPM1-E192K knock-in human induced pluripotent stem cell line using CRISPR/Cas9 system. Stem Cell Res. 2022 Aug;63:102878. | 외부링크연결 | ||
| Jung SY et al. Wnt-activating human skin organoid model of atopic dermatitis induced by Staphylococcus aureus and its protective effects by Cutibacterium acnes. iScience. 2022 Sep 16;25(10):105150. | 외부링크연결 | ||
| Mun D et al. Generation of two PITX2 knock-out human induced pluripotent stem cell lines using CRISPR/Cas9 system,. Stem Cell Res. 2022 Dec;65:102940. | 외부링크연결 | ||
| Jeon SB et al. Human induced pluripotent stem cell line YCMi007-A generated from a dilated cardiomyopathy patient with a heterozygous dominant c.613C>T (p.Arg205Trp) variant of the TNN2 gene. Stem Cell Res. 2023 Mar;67:103048. | 외부링크연결 | ||
| CMC-hiPSC-022 |
특허출원 : HLA 동형접합체의 제대혈단핵구세포 유래 인간전분화능세포를 이용한 연골세포 분화용 조성물 제조방법, 출원인 : 주지현 등, 출원번호 : 10-2017-0178684, 출원일자 : 2017년 12월 22일 |
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| Kim JH et al. Korea National Stem Cell Bank. Stem Cell Res. 2021 May;53:102270. | 외부링크연결 | ||
| NU01-EiPS07 | Im YS et al. Generation of integration-free induced pluripotent stem cell line (KSCBi012-A) from urinary epithelial cells of a healthy male individual. Stem Cell Res. 2022 Aug;63:102841. | 외부링크연결 | |
| PB01-EiPS21 | Im YS et al. Generation of integration-free induced pluripotent stem cell line (KSCBi017-A) from peripheral blood mononuclear cells of a healthy male individual. Stem Cell Res. 2022 Dec;65:102965. | 외부링크연결 |
Disease-Specific hiPSC
| 종류 | 세포주 명 | 참고문헌 | DOI Link |
|---|---|---|---|
| Disease -Specific hiPSC |
DKH005i-A | Park et al. Generation of human induced pluripotent stem cells from peripheral blood mononuclear cells of a Senior-Loken syndrome patient. Stem Cell Res. 2019 Dec;41:101648. | 외부링크연결 |
| Kim JH et al. Korea National Stem Cell Bank. Stem Cell Res. 2021 May;53:102270. | 외부링크연결 | ||
| DKH090i-A | Kim JH et al. Korea National Stem Cell Bank. Stem Cell Res. 2021 May;53:102270. Park et al. Generation of a human induced pluripotent stem cell line from a patient with Leber congenital amaurosis. Stem Cell Res. 2020 Mar;43:101725. | 외부링크연결 | |
| Kim JH et al. Korea National Stem Cell Bank. Stem Cell Res. 2021 May;53:102270. | 외부링크연결 | ||
| LQT01-hiPSC | Lee Y et al. Establishment of a human induced pluripotent stem cell line, KSCBi015-A, from a long QT syndrome type 2 patient harboring a KCNH2 mutation. Stem Cell Res. 2021 Oct 13;57:102570. | 외부링크연결 | |
| LQT08-hiPSC | Lee Y et al. Establishment of a human induced pluripotent stem cell line, KSCBi015-A, from a long QT syndrome type 1 patient harboring a KCNQ1 mutation. Stem cell research. 2021 Oct;56:102521. | 외부링크연결 |
Fluorescent protein-tagged hiPSC
| 종류 | 세포주 명 | 참고문헌 | DOI Link |
|---|---|---|---|
| Fluorescent protein-tagged hiPSC | NCRM5AS1-iCAGcGFP.c9 | Luo et al. Stable enhanced green fluorescent protein expression after differentiation and transplantation of reporter human induced pluripotent stem cells generated by AAVS1 transcription activator-like effector nucleases. Stem Cells Transl Med. 2014 Jul;3(7):821-35. | 외부링크연결 |
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특허출원 : 대뇌 오가노이드-모터뉴런 스페로이드 구조체 및 이의 제조방법, 출원인 : 최정우 등, 출원번호 : 10-2020-0154027, 출원일자 2020년 11월 17일 |
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| Kim JH et al. Korea National Stem Cell Bank. Stem Cell Res. 2021 May;53:102270. | 외부링크연결 | ||
| CMC-003i-Nestin.EGFP | Lee Y et al. Generation of a NESTIN-EFGP reporter human induced pluripotent stem cell line, KSCBi005-A-1, using CRISPR/Cas9 nuclease. Stem. Cell Res. 2019 Oct;40:101554. | 외부링크연결 | |
| Kim JH et al. Korea National Stem Cell Bank. Stem Cell Res. 2021 May;53:102270. | 외부링크연결 | ||
| CMC-003i-Pdx1.EGFP | Lee Y et al. Generation of a PDX1-EFGP reporter human induced pluripotent stem cell line, KSCBi005-A-3, using CRISPR/Cas9 system. Stem Cell Res. 2019 Dec;41:101632. | 외부링크연결 | |
| Kim JH et al. Korea National Stem Cell Bank. Stem Cell Res. 2021 May;53:102270. | 외부링크연결 |
Gene-Edited hiPSC
| 종류 | 세포주 명 | 참고문헌 | DOI Link |
|---|---|---|---|
| Gene-Edited hiPSC | hiPSC-TLR2KO | Han HJ et al. Generation of a TLR2 knockout human induced pluripotent stem cell line using CRISPR/Cas9. Stem Cell Res. 2021 Oct 19;57:102578. | 외부링크연결 |
| hiPSC-TLR3KO-A49 | Han HJ et al. Establishment of a TLR3 homozygous knockout human induced pluripotent stem cell line using CRISPR/Cas9. Stem Cell Res. 2021 Apr;52:102187. | 외부링크연결 | |
| hiPSC-TLR7KO-A59 | Han HJ et al. Generation of a TLR7 homozygous knockout human induced pluripotent stem cell line using CRISPR/Cas9. Stem Cell Res. 2019 Oct;40:101520. | 외부링크연결 | |
| hiPSC-TLR8KO-A10 | Han HJ et al. Generation of a KSCBi005-A-5(TLR8KO-A10) homozygous knockout human induced pluripotent stem cell line using CRISPR/Cas9. Stem Cell Res. 2019 Oct;40:101561. | 외부링크연결 | |
| hFSiPS1_DUSP6KO |
특허출원 : DUSP6가 결핍된 줄기세포 및 이의 용도 (DUSP6 deficient stem cells and their use), 출원인 : 국립보건연구원장, 출원번호 : 10-2022-0073479, 출원일자 : 2022년 6월 16일 |
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| Yoo DH et al. DUSP6 is a memory retention feedback regulator of ERK signaling for cellular resilience of human pluripotent stem cells in response to dissociation. Sci Rep. 2023 Apr 7;13(1):5683. | 외부링크연결 | ||
| hFSiPS1_DUSP6KOA |
특허출원 : DUSP6가 결핍된 줄기세포 및 이의 용도 (DUSP6 deficient stem cells and their use), 출원인 : 국립보건연구원장, 출원번호 : 10-2022-0073479, 출원일자 : 2022년 6월 16일 |
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| Yoo DH et al. DUSP6 is a memory retention feedback regulator of ERK signaling for cellular resilience of human pluripotent stem cells in response to dissociation. Sci Rep. 2023 Apr 7;13(1):5683. | 외부링크연결 |