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Clinical Research Information Service (CRIS)

Update

2026-05-13

Clinical Research Information Service (CRIS)

CRIS

1. Overview

The Clinical Research Information Service(CRIS) is a non-profit, web-based clinical research registry established to promote transparency, accountability, and ethical standards in clinical research conducted in the Republic of Korea.

CRIS registers prospective clinical trials and clinical research involving human participants that aim to prevent, detect, diagnose, or treat diseases. All studies must receive Institutional Review Board (IRB) approval prior to registration.

CRIS is operated by the Korea Disease Control and Prevention Agency (KDCA) with support from the Ministry of Health and Welfare (MOHW). Since 2010, CRIS has served as the 11th Primary Registry of the World Health Organization (WHO) International Clinical Trials Registry Platform (ICTRP).

2. Contents

  • Registration of IRB-approved clinical trials and clinical research conducted in Korea
  • Assignment of a unique CRIS registration number (KCT number)
  • Public disclosure of registered study information in real time
  • Provision of searchable database and statistical summaries
  • Data sharing with the WHO ICTRP to support global research transparency

3. Registration Status

As of December 31, 2025, a total of 12,396 clinical studies have been submitted to CRIS. Of these, 11,376 studies have completed content review and have been formally registered.

Year 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025
Submission 451 507 571 999 1,012 1,237 1,200 1,231 1,169 1,114 1,374
Registration 412 430 435 788 1,181 1,140 1,155 1,173 1,031 1,010 1,298
Cumulative Number 1,735 2,165 2,600 3,388 4,569 5,709 6,864 8,037 9,068 10,078 11,376

CRIS

The Clinical Research Information Service

For More information, visit the CRIS

website:
https://cris.nih.go.kr
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