Korea Biobank Network
detail content area
Korea Institute of Radiological and Medical Sciences (KIRAMS)
As a pioneer of national radiological medicine, the KIRAMS started out as the Institute of Radiation Medicine Research Center in 1963. It was reorganized as the Korea Cancer Center Hospital in 1973 and then as the Radiation Medical Center in 2002. In 2007, it was reborn as the KIRAMS under the Ministry of Education, Science, and Technology, with several divisions, including the Korea Cancer Center Hospital (KCCH), Institute of Radiation Medicine Research Center, and National Emergency Medical Dispatch Center. Living up to its reputation as a leader in advanced cancer diagnosis and treatment, the KIRAMS was the first hospital in Korea to introduce radiology cancer treatment using cobalt remote treatment. The KIRAMS is also ushering in a new age of bloodless cancer surgery in the country by launching CyberKnife. It also introduced the first Cyclotron, a circular accelerator, in Korea, and firmly established the foundation for research projects aimed attreating various types of cancer, including treatment and early diagnosis using radioisotopes. In particular, the KIRAMS takes great pride in its effective diagnosis system that fosters close cooperation among highly talented cancer specialists.
The KIRAMS Radiation Biobank (KRB) was approved for opening by the Ministry of Health and Welfare in 2011, and has since been collecting, storing, and distributing human bioresources, including specialized blood biospecimens, from cancer patients, patients receiving radiation treatment, and radiation-related workers. Leftover blood specimens from patients who have blood tests in KCCH are collected to be used to support research in radiological medicine or cancer medicine. The KRB is supplementing SOPs in accordance with revisions to bioethics legislation and cooperating closely with domestic and overseas biobanks. This effort will allow researchers to conduct medical research more ethically and with fewer difficulties.
- 2004–2006: Radiation Biorepository Information Center Program
- 2007–2010: Radiation Biospecimen Bank
- April 2011: Approval for the opening of gene bank; hosting of KIRAMS Radiation Biorepository Bank Seminar
- April 2012: Hosting of joint seminar with Chernobyl Tissue Bank
- December 2012: MOU agreement with the Gwandong Medical School Cheil Medical Center
- January 2013: MOU agreement with the National Research Institute of Korea
- March 2013: Approval for the opening of biobank
- May 2013: Participation in Phase 2 of the KBP
- July 2015 : Installation of the Human Biobank Information System(HuBIS_Sam) program
- December 2017 : Participation in HuBIS-Desk, a web portal for human bioresource distribution
Current Status of Human bioresources
The KRB collects leftover blood specimens from patients who have blood tests in KCCH; the blood is separated into plasma, serum, buffycoat, DNA, and cells for storage. The KRB's bank mainly acquires blood specimens from individuals working with radiation (including information on working period and work type) and radiation therapy patients (breast, colon, lung, thyroid, and gastric cancer, among others), and provides support for radiological medicine intervention studies.
Currently (as of December 31, 2019), the bank has secured blood specimens from a total of 42,936 individuals (156,878 vials), including 820 individuals who work with radiation (2,585 vials).
Projects and Distribution Results
Blood specimens from radiation workers, radiation therapy patients, and patients with lung cancer, multiple myeloma, breast cancer, and colon cancer have been distributed to internal and external researchers. Since 2011, a total of 69 studies (up to December 31, 2019) have received support in the form of blood specimens.
Public Relations and Future Plans
The KRB advertises itself to patients and targets for health examinations through the distribution of pamphlets and installation of booths in radio-oncology departments and general cancer health check-up centers. The KRB's publicity video is broadcast within the hospital to inform visitors of the importance of donating leftover blood. Further, by regularly participating in work experience programs for the youth, the KRB promotes awareness and participation in human resource donation through visits to the biobank and experience with experiments. To increase resource distribution, pamphlets are distributed in symposia and external seminars. Moreover, the KRB hosts a website that provides researchers with convenient updates of the status of biospecimens and allows easy application for distribution. Resource information is updated every month.
Close collaborative relationships are maintained domestically and overseas, such as the exchange of academic and technological information with the Chernobyl Tissue Bank and joint use of biospecimens for technological development related to disease diagnosis and treatment.
KIRAMS Radiation Biobank, No. 1511, 5F Research Building #2, Korean Institute of Radiological and Medical Sciences, 75 Nowon-ro, Nowon-gu, Seoul, Korea (01812)
- E-mail: firstname.lastname@example.org