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The Korean Acute Heart Failure Registry(KorAHF)

The prevalence of heart failure in Korea, and its influence on mortality, morbidity, and the cost of health care, has been rapidly increasing. To reduce the health burden of heart failure, and to improve the care system and clinical guidelines, it is essential to verify the patient profile, current trends in management, and outcomes. The Korean Acute Heart Failure registry (KorAHF) aims to evaluate clinical characteristics, management, hospitalization course, predictors of mortality, and short-term and long-term outcomes of patients hospitalized for acute heart failure syndrome (AHFS) in Korea. Patients hospitalized for AHFS were consecutively enrolled in 10 tertiary hospitals across the country from March 2011 to March 2014. In total, 5,625 patients were enrolled in this registry. The patients are expected to attend follow-up until 2016. Data management and audit have been performed for QC of the registry. The case report form has been upgraded, based on the results from data management and audit. Interim analysis of the 5,625 patients was performed. This analysis aimed to investigate baseline characteristics, management, short-term outcomes, and predictors of in-hospital mortality. The mean age of patients was 69±15 years, 53% were male, 52% had de novo heart failure, 59% had hypertension, and 35% had diabetes mellitus. Ischemia was both the leading cause (37%) and the most frequent aggravating factor (26%) of AHFS. Parenteral diuretics and inotropic agents were administered in 75% and 31% of patients, respectively. Angiotensin-converting enzyme inhibitors/ angiotensin receptor blockers and beta-blockers were prescribed at discharge in 70% and 53% of the patients, respectively. The mean length of hospital stay was 9 days and the mean cost for an admission was about 10,000,000 Korean Won. In-hospital mortality was 5.9%. The post-discharge 90-day all-cause mortality and the readmission rate due to heart failure were 8.7% and 14%,respectively. Through studying the characteristics and associated causes of heart failure, a foundation for evidence-based disease management can be established. Moreover, we could improve prognosis via the active management of heart failure, and draw on the underlying data to assess the economic feasibility of this. All the activities of KorAHF could be very helpful for the establishment of public health policies in the future..

[Table 1. Characteristics of patients enrolled in KorAHF]