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High-level mupirocin resistance in Gram-positive bacteria isolated from diseased companion animals
  • 작성일2021-02-17
  • 최종수정일2021-02-17
  • 담당부서연구기획과
  • 연락처043-719-8033
  • 38

Journal of Veterinary Science, 2020.21(3), 1-8, DOI: https://doi.org/10.4142/jvs.2020.21.e40


High-level mupirocin resistance in Gram-positive bacteria isolated from diseased companion animals

Sum Samuth, Hee-Myung Park, and Jae-Young Oh*


Abstract

    The purpose of this study was to investigate the high-level mupirocin resistance (HLMR) in Gram-positive bacteria isolated from companion animals. A total of 931 clinical specimens were collected from diseased pets. The detection of mupirocin-resistant bacteria and plasmid-mediated mupirocin resistance genes were evaluated by antimicrobial susceptibility tests, polymerase chain reactions, and sequencing analysis. Four-hundred and six (43.6%) bacteria were isolated and 17 (4.2%), including 14 staphylococci and 3 Corynebacterium were high-level mupirocin-resistant (MICs, ≥ 1,024 ug/mL) harboring mupA. Six staphylococci of HLMR strains had plasmid-mediated mupA-IS257 flanking regions. The results show that HLMR bacteria could spread in veterinary medicine in the near future.



  • 본 연구는 질병관리본부 연구개발과제연구비를 지원받아 수행되었습니다.
  • This research was supported by a fund by Research of Korea Centers for Disease Control and Prevention.


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