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International journal of infectious diseases, 2020.92, 53-55, DOI: https://doi.org/10.1016/j.ijid.2019.12.025
Increasing prevalence of multidrug-resistant mcr-1-positive Escherichia coli isolates from fresh vegetables and healthy food animals in South Korea
Sung-Suck Oh, Jihyun Song, Junghee Kim, Jinwook Shin
Colistin is a last-resort antimicrobial against multidrug-resistant gram-negative bacteria. The occurrence and spread of colistin resistance in humans and animals have been reported globally. This study was performed to investigate the prevalence and antimicrobial susceptibility of mcr-harboring colistinresistant Enterobacteriaceae from retail vegetables and food animals in South Korea in 2018. The mcr-1 gene was detected in Escherichia coli isolates from 0.076% (1/1324) of vegetables, 5.9% (2/34) of chickens, 6.8% (4/59) of pigs, and 0% (0/57) of cattle. Other mcr genes were not detected. All seven of the mcr-1-positive isolates showed multidrug resistance and co-produced β-lactamases. Multilocus sequence typing analysis revealed five known E. coli sequence types (STs), including ST10 in the vegetable sample. The study findings demonstrated that the mcr-1 gene has emerged in vegetables and is increasingly detected in food animals in South Korea, highlighting the importance of continuous monitoring and control of colistin-resistant Enterobacteriaceae to prevent them from being transmitted to humans.
- DOI: https://doi.org/10.1016/j.ijid.2019.12.025
- ISBN or ISSN: 1201-9712
- 본 연구는 질병관리본부 연구개발과제연구비를 지원받아 수행되었습니다.
- This research was supported by a fund by Research of Korea Centers for Disease Control and Prevention.