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First case of fungla corneal ulcer caused by Pestalotiopsis mangiferae
  • 작성일2021-02-08
  • 최종수정일2021-02-08
  • 담당부서연구기획과
  • 연락처043-719-8033
  • 84

Laboratory Medicine Online, 2020.10(2), 247-249, DOI: https://doi.org/10.3313/lmo.2020.10.3.247


First case of fungla corneal ulcer caused by Pestalotiopsis mangiferae

Roh Soongki, Myungchul Suh, Hyun Chul Lee, Won-Kil Lee, Yu Kyung Kim


Abstract

    Pestalotiopsis species are filamentous fungi that are known plant pathogens commonly isolated in tropical and subtropical regions. To the best of our knowledge, this is the first case of human infection caused by Pestalotiopsis mangiferae. An 80-year-old male farmer presented with ocular pain in the right eye. At initial presentation, slit-lamp examination showed a 3.0×2.5 mm-sized epithelial defect in the cornea of the right eye accompanied by corneal thinning. A KOH examination revealed spores, and consequently, treatment with voriconazole, ceftazidime, and moxifloxacin was initiated. One month later, a second KOH examination and fungal culture were performed. The results of the KOH examination indicated the presence of many hyphae, and fungus was isolated from the culture. Molecular identification revealed that the sequence had 100% similarity to P. mangiferae. The patient was treated with therapeutic penetrating keratoplasty. During follow-up in the outpatient clinic, signs of infection were not observed.



  • 본 연구는 질병관리본부 연구개발과제연구비를 지원받아 수행되었습니다.
  • This research was supported by a fund by Research of Korea Centers for Disease Control and Prevention.


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