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대한내과학회지, 2019. 94(1), 96-106, DOI: https://doi.org/10.3904/kjm.2019.94.1.96
고령의 급성 심근경색증 환자에서 성별에 따른 영향
설수영, 정명호; 이승헌; 손석준; 조재영; 김민철; 심두선; 홍영준; 박형욱; 김주한; 안영근; 조정관; 박종춘
Background/Aims: It is well known that gender differences are associated with clinical outcomes in patients with acute myocardialinfarction (AMI). However, it is not clear whether gender differences affect the prognosis of elderly patients with AMI.
Methods: We analyzed the incidence of in-hospital complications and mortality in the Korea Acute Myocardial InfarctionRegistry-National Institutes of Health from November 2011 to June 2015. This study included elderly patients (≥ 75 years) diagnosedwith AMI.
Results: A total of 2,953 patients were eligible for this study. Among them, 1,529 (51.8%) patients were female, and the mean ageof the female group was older than that of the male group (80.7 ± 4.4 vs. 79.6 ± 4.0 years, respectively, p < 0.001). Elderly femalesutilized emergency medical services less frequently compared with elderly males (11.5 vs. 15.4%, respectively, p < 0.001). Elderlyfemale AMI patients had a similar rate of in-hospital mortality compared with elderly males (7.1 vs. 8.4%, respectively, p = 0.196).The rate of major cardiac adverse events (MACEs) was lower in elderly females than males during a 12-month follow-up (hazardratio [HR] 1.19, 95% confidence interval [CI] 1.00-1.41, p = 0.045). According to multivariate analysis, the male gender is an independentfactor for predicting 1-year MACEs (HR 1.37, 95% CI 1.14-1.65, p < 0.001).
Conclusions: No significant differences in peri-procedural complications or in-hospital mortality were observed between male andfemale elderly patients with AMI. However, elderly female patients had a more favorable prognosis than male patients during a1-year clinical follow-up.
- DOI: https://doi.org/10.3904/kjm.2019.94.1.96
- ISBN or ISSN: 1738-9364
- 본 연구는 질병관리본부 연구개발과제연구비를 지원받아 수행되었습니다.
- This research was supported by a fund by Research of Korea Centers for Disease Control and Prevention.