detail content area
BMJ Open, 2019. 9, e031018-, DOI: https://doi.org/10.1136/bmjopen-2019-031018
Cohort profile: Korean Urban Rural Elderly (KURE) study, a prospective cohort on ageing and health in Korea
Namki Hong, Kwang-Joon Kim; Su Jin Lee; Chang Oh Kim; Hyeon Chang Kim; Yumie Rhee; Yoosik Youm; Jin-Young Choi; Hyun-Young Park
Purpose: The Korean Urban Rural Elderly (KURE) cohort was initiated to study the epidemiologic characteristics, physical performance, laboratory and imaging biomarkers and incidence of age-related diseases in an elderly population with respect to both clinical and social aspectsto develop preventive and therapeutic strategies forcombatting age-related diseases.
Participants: A total of 3517 adults aged 65 or older participated in the cohort at baseline from 2012 to 2015, recruited from three urban districts and one rural districtin Korea. The second-wave follow-up survey is now being conducted at a 4-year interval from baseline (2016–2019; follow-up rate 71.5%). The data set included detailed information on anthropometric and socioeconomic factors, functional assessments, image scans (plain radiography, dual-energy X-ray absorptiometry and CT), biospecimens(ie, serum, urine and DNA) and social support networks along with the feasibility of linkage to a national claims database.
Findings to date: Mean age of participants at entry was71.9±4.6 years and 67% were women. From the KURE participants enrolled in baseline recruitment, several studies were published in the fields of cardiometabolic diseases, musculoskeletal health and the association between social support network and diseases in ageing.
Future plans: Participants will be observed actively andpassively every 4–5 years and the first follow-up willbe completed in 2020. The KURE data set has strength in comprehensive physical function assessments, quantifiable imaging data sets using CT and detailed information regarding the social support networks of participants from a large community-based elderly Korean population.
- DOI: https://doi.org/10.1136/bmjopen-2019-031018
- ISBN or ISSN: 2044-6055
- 본 연구는 질병관리본부 연구개발과제연구비를 지원받아 수행되었습니다.
- This research was supported by a fund by Research of Korea Centers for Disease Control and Prevention.