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Alcohol, 2019. 77, 19-25, DOI: https://doi.org/10.1016/j.alcohol.2018.09.002
Association between alcohol intake and incident hypertension in the Korean population
Min-Gyu Yoo, Keon Jae Park;Hyo-Jin Kim;Han Byul Jang;Hye-Ja Lee;Sang Ick Park
Background and aims:
Alcohol consumption is generally associated with increased risk of hypertension.However, the effect of alcohol intake on the incidence of hypertension remains controversial due toinconsistent results across studies. We investigated the association between alcohol intake and hypertensionin a Korean population.
Methods and results:
The two studies that we evaluated herein, the CAVAS study (N ¼ 6259) and theAnsan-Ansung study (N ¼ 2461), were part of the Korean Genome and Epidemiology study on participantsaged between 40 and 69 years who underwent community-based health checkups (2 years for theCAVAS study follow-up and 12 years for the Ansan-Ansung study follow-up). We categorized the participantsinto four groups based on baseline and follow-up period measurements.We found that baselinealcohol consumption increased the risk of incident hypertension in the CAVAS study [HR (95% CI), low:1.094 (0.848e1.411); intermediate: 1.661 (1.227e2.141); high: 1.723 (1.274e2.330)]. Intermediate andhigh alcohol consumption were associated with increased risk of incident hypertension in men [2.086(1.438e3.027) for intermediate, and 1.952 (1.294e2.944) for high], but only women had increased risk ofincident hypertension with high consumption [1.950 (1.100e3.455)]. In addition, we found a positiveassociation between the alcohol consumption pattern (over 10 years) and the risk of incident hypertensionin the Ansan-Ansung study [HR (95% CI), light: 1.316 (1.126e1.539); moderate: 1.445 (1.193e1.750); heavy: 1.897 (1.488e2.419)]. Moderate and heavy consumption patterns carried higher risks ofincident hypertension compared with never-drinking in men [moderate: 1.292 (1.033e1.617); heavy:1.703 (1.293e2.242)], but women with light consumption patterns were at increased risk of incidenthypertension [1.572 (1.302e1.899)].
This large prospective cohort study revealed a linear association between baseline alcoholconsumption, subsequent alcohol consumption patterns (over more than 10 years), and hypertensionrisk in the Korean population.
- DOI: https://doi.org/10.1016/j.alcohol.2018.09.002
- ISBN or ISSN: 0741-8329
- 본 연구는 질병관리본부 연구개발과제연구비를 지원받아 수행되었습니다.
- This research was supported by a fund by Research of Korea Centers for Disease Control and Prevention.